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15(11):21419-32
EMT inhibitor-1 (C19) (intraperitoneal injection
inhibiting phosphorylation of P-Smad3 by TGFβR-I Kinase with Ki of 28 nM
PubMed PMID: 26388514
1021/jm5014055
Ripasudil HCl dihydrate - CAS# 887375-67-9 012 15(11):21419-32Ripasudil HCl dihydrate, CAS No. 887375 67 9, is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. Product information CAS Number: 887375 67 9 Molecular Weight: 395. 88 Formula: C15H23ClFN3O4S Synonym: K 155 K115 Glanatec Ripasudil HCl dihydrate Related CAS Number: 223644 02 8 (HCl) 223645 67 8 (free base) Chemical Name: (S) 4 fluoro 5 ((2 methyl 1,4 diazepan 1 yl)sulfonyl)isoquinoline hydrochloride dihydrate