5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)sulfanyl]methanimidamide
and induces apoptosis in PANC-1 cells
HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22
Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest
IL-1β and TNF-α by comparation with ZEA or α-Zearalenol
MS417 Catalog No.:M14631-2 5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)sulfanyl]methanimidamideMS417 is a selective BET specific BRD4 inhibitor, binds to BRD4 BD1 and BRD4 BD2 with IC50s of 30, 46 nM and Kds of 36. 1, 25. 4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32. 7 M). Product information CAS Number: 916489 36 6 Molecular Weight: 414. 91 Formula: C20H19ClN4O2S Chemical Name: methyl 2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12 pentaen 9 yl]acetate Smiles: