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No cellular activity is observed for SGC2085 when tested up to 10 μM (48 h exposure in HEK293 cells)
Mice are treated with two-fold increasing doses (range 3
PR5-LL-CM01 inhibits NF-κB activation and its target gene expression in PDAC and CRC cells
Solubility: H2O : ≥ 100 mg/mL (195
InChiKey: RTLULCVBFCRQKI-UHFFFAOYSA-N
(S)-CFT7455 tinib bromide No cellular activity is observed(S) CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S) CFT7455 is an anti cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0. 9 nM)(WO2022032132A1; Compound 1). Product information CAS Number: 2504235 67 8 Molecular Weight: 469. 53 Formula: C28H27N3O4 Smiles: O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O InChiKey: MUKCJOOKCZSQNW DEOSSOPVSA N