APC Mouse Monoclonal Antibody(ARA727) Cell Culture Slides Jan 2010] Swissprot No P26927

Jan 2010] Swissprot No P26927 Gene Accession 4485 WB Predicted band size 80 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm and Nucleus IHC positive control Positive control: Human colon cancer IHC Recommed dilution Recommended dilution: 50-100 Storage

P114234-WB-1-P

DNA Dilution Buffer (NND001) 1

translation

25 pg/mL – 2000 pg/mL Recovery 84% – 120% Average Recovery 102% Intra Precision 4

APC Mouse Monoclonal Antibody(ARA727) Cell Culture Slides Jan 2010] Swissprot No P26927Background This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region