Anyone who has seen this deck in action knows that if both of these creatures remain on the battlefield for even a single turn, the game usually ends due to each rune also functioning as a cantrip (a card that replaces itself)
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The ability to exile a Pithing Needle on Teferi, Hero of Dominaria, a Goblin Guide against Burn, and a Relic of Progenitus shutting down your graveyard makes the card an appealing sideboard option for control decks, especially those with Snapcaster Mage, and the fact that Isolate is so efficient and hits such a wide range of targets means that it is certainly in the sideboard conversation for other decks as well
*The variant cards from Unstable are kind of an exception here
in the United States and Konami Digital Entertainment B.V
