For example, Karador, Ghost Chieftain wants to tap out on your turn, and the two cards are simply antithetical
Secret Rare - Gold Holo Foil

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Do you take damage to keep up interaction and signal it
Jace's Defeat is a card that's actively better against Jace planeswalkers, as part of a cycle from Hour of Devastation depicting the defeat of key characters
In most cases (see below), if you wait until the combat damage step or end of combat step, it will be after combat damage has been dealt, so the Ninja won't deal combat damage