You can have emptied your hand on turn two and be ready to use your spare mana to tie up theirs with little to no impact on your curve at all
This list focuses on cards that can put counters on themselves and others, with a bias towards Commander and Cube, though all-stars in other formats can show up
Triomes with the Forest type like Ketria Triome are also slightly better since they can be found with cards like Nature's Lore or Skyshroud Claim
Obviously, having these cards legal in any Arena format would be a bit of a problem, so this uncollectible approach by Wizards makes sense
First off all, it exiles, preventing your opponent benefitting from pesky death triggers
Sometimes on early turns a Bloodghast is all you have in your graveyard, and if you have a big dredge planned for the following turn, its sometimes better to just leave it in the graveyard so it can return Prized Amalgams later