Uro, Titan of Nature's Wrath | Illustration by Vincent Proce Simic creatures in MTG have a green-blue, or Simic color identity
Spiders gum up the board and protect your life total reasonably well, which lets you spend life more liberally to maximize Connections
Spells such as Duel for Dominance buff your creatures before they fight an opponent's creature
If your initial draw gives you The Queen, Commanding Prescene, its worth throwing everything else out to get The Queen, Regal Monarch
But when you need a board wipe, you can use the Exude Toxin omen, dropping a powerful -X/-X effect that wipes out smaller non-dragon creatures
This puts them in a lose-lose situation: pay an extra mana tax on all noncreature spells or let you draw free cards