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You can sacrifice a Clue tokens whenever you have priority and can pay the activation cost (usually )

You also need to watch if your creatures have taken lethal damage and an opponent can remove Darksteel Forge from the battlefield, either exiling it or putting it back in your hand, which will cause all your creatures to die to state-based actions

There are much better options for Commander decks that may want this for other reasons, though

It is, itself, a 2/2, and it can produce a bunch more 2/2s (likely after a sweeper), so it powers your synergies with Dusk // Dawn, Return of the Wildspeaker, and more

While you may think of activated abilities as something that cards on the battlefield use, like lands tapping for mana or planeswalkers using their abilities, theres actually no reason why we cant have abilities that activate from other zones

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