Between this and the philosophy that multicolor cards can draw upon multiple parts of the color pie for their effects, the roles of multicolor cards are somewhat more malleable than those of their monocolor counterparts, as recently demonstrated by Wizards of the Coast when designing the colleges of Strixhaven
The only other main difference is that Commander damage is a thing
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Tiamat [Foil] #235 Magic Adventures in the Forgotten Realms Keep track of your collection value over time
Jaya's Immolating Inferno As you may have realized, dealing damage to multiple targets can be difficult as you need to pay a lot of mana for it