It's a little bit less of a perfect fit than Edea deflecting a bullet, but if you think of it as destroying the universe = denying the arcane, it kind of gets the job done
If you can put some poison counter-generating cards like Infectious Inquiry and Ichor Rats into your deck, Yawgmoth can proliferate those as well, though this does risk making you public enemy number one at your table
Could Be Fun : These commanders are powerful and don't pull you in a single direction, but because of that, it allows you to build weird strategies with a powerful engine, or have unique build paths that could work
As you can see, the dork is a nasty on curve 6/5 trampler who can win you the game
Cloud from Final Fantasy VII Cloud works well if he has Equipment
Without spell slinging, it doesn't do much, and unlike the others you don't get a rebate from this