If you have drawn four or five cards, that's mana you can use to cast some of those cards
Spreading the Poison to multiple opponents also works great with both of the Commanders from the Corrupting Influence Precon Ixhel, Scion of Atraxa and Vishgraz, the Doomhive, both of whom benefit from having many Poison Counters in play, with Ixhel specifically wanting each opponent to have three or more
Taking out Zetalpa, Primal Dawn is a pretty obvious choice since the card does nothing to further the strategy of your deck
It also combos well with board wipes or Nevinyrral's Disk-style effects to let you clear the board while you keep your own stuff intact
Such a wacky choice for an enchantment, and I wonder if this was originally artwork commissioned for a creature
With such a high influx of valuable reprints mingled with the creatures and spells of The Brothers War, there are plenty of high-value cards for you to collect