PROTAC PD-1/PD-L1 degrader-1 Size:100 mg solid Experimental Anti-Inflammatory Drug Semapimod Inhibits

Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96

Formula: C16H16N2O3S

LC-2-induced KRASG12C degradation occurs via a bona fide PROTAC mechanism

Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy

Lassalle G

PROTAC PD-1/PD-L1 degrader-1 Size:100 mg solid Experimental Anti-Inflammatory Drug Semapimod InhibitsPROTAC PD 1 PD L1 degrader 1, a PD 1 PD L1 degrader, inhibits PD 1 PD L1 interaction with an IC50 of 39. 2 nM. PROTAC PD 1 PD L1 degrader 1 significantly restores the immunity repressed in a co culture model of Hep3B OS 8 hPD L1 and CD3 T cells. PROTAC PD 1 PD L1 degrader 1 moderately reduces the protein levels of PD L1 in a lysosome dependent manner. Product information CAS Number: 2447066 37 5 Molecular Weight: 1076. 59 Formula: C59H58ClN7O11