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CHIR99021 - GSK3β Inhibitor. CAS# 252917-06-9 Catalog No.:M60002-25S 14: 1363-1369

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Description

14: 1363-1369

EtOH up to 100 mM

AK-7 was used at 10-25 µM in vitro and in cellular assays

Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma

(2008) Biochem J

CHIR99021 - GSK3β Inhibitor. CAS# 252917-06-9 Catalog No.:M60002-25S 14: 1363-1369CHIR99021, CAS No. 252917 06 9, is the most widely used, potent and selective inhibitor of glycogen synthase kinase 3 (GSK3) with an IC50 ~7 nM. It can effectively activate Wnt signaling pathway in various cellular systems. CHIR99021 has been shown to enhance the reprogramming of murine and human somatic cells into iPSCs, potently promote expansion of embryonic stem cells and tissue specific adult stem cells (such as hematopoietic stem and progenitor

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