Vigilance doesnt create any special rules for blocking
My biggest issue here is that theres not an obvious spot to play it where it has a meaningful impact
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Her ability specifically dictates that Doctor abilities trigger twice (and surprise, surprise, all the Doctors have triggered abilities)
This gives you less reason to keep the Plains because you want a density of threats to fight through a slower deck, and the game is also more likely to get to a point where you naturally draw seven lands over time
The Frenzy version is still favored, especially as it plays more burn spells, but the four-drops arent good in this matchup